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We also postulate that increased natriuretic after liraglutide in severe diabetic kidney disease may result from increased atrial natriuretic peptide secretion and decreased aldosterone secretion

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1,2 A serious allergic reaction to a GLP-1 medication If youve previously had a severe allergic reaction to tirzepatide, semaglutide, liraglutide, or any other GLP-1 medication, you shouldnt be re-prescribed one
Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Sitagliptin as an Add-on to Metformin, Thiazolidinediones, or Both, in Patients With Type 2 Diabetes (SUSTAIN 2): A 56-Week, Double-Blind, Phase 3a, Randomised Trial

NICE recommends it for adults with a BMI 30 kg/m, or 28 kg/m in the presence of associated risk factors such as type 2 diabetes or hypertension
