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Description
This results in a rise in glucose levels in the end part of the intestine, which then triggers an increase in the release of GLP-1 from L cells, promoting growth (Wu et al., 2017)
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It often comes back abruptly, and many patients describe it as one of the hardest parts of discontinuation
Clinical trials have yielded mixed results: several studies, including a phase II trial of NLY01, failed to meet primary endpoints for motor progression, with only modest or nonsignificant effects overall [37,38]
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Diabetes 68, 2133 (2019)
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