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Glucagon, by contrast, raises energy expenditure and mobilizes fat for fuel

After you eat, your intestinal L-cells release GLP-1, which signals to your brain, pancreas, and digestive tract that food has arrived

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Hyperstack images were captured using a 63X objective lens on a spinning disk confocal microscope (PerkinElmer-Cetus, Norwalk, CT)

Direct contact of nutrients with intestinal L-cells on the apical intestinal lumen produces an initial secretory peak as early as 1015 min after consumption of a meal, followed by a secondary peak around 3060 min post-consumption [11]