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Now, TRPV1 is also deeply involved in central sensitisation and hyperalgesia in fibromyalgia, so thats a mechanistically plausible connection

This microbiome effect may partly explain why berberine works better in some individuals than others

Participants in the STEP 1 trial regained almost two-thirds of their original weight loss after stopping weekly subcutaneous semaglutide (Wegovy) 2.4 mg and lifestyle modifications for a year
