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Description
This multi-receptor action sets retatrutide apart from existing GLP-1 receptor agonists like semaglutide (Ozempic or Wegovy) and dual agonists like tirzepatide (Mounjaro or Zepbound)

Oxyntomodulin is generated by post-translational processing of the glucagon precursor, proglucagon, in the intestine

Understanding energy changes on semaglutide requires looking at the whole picture, not just one variable

The physical transformation is the easy part

-10.9% lean body mass over 72 weeks) per the SURMOUNT-1 body-composition substudy [12]

To view a copy of this licence, visit About this article Cite this article Andersen, A., Knop, F.K
