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All other domains, including randomization, blinding, outcome measurement, and selective reporting, were rated as low risk across all included studies

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Although these side effects sound scary, most people only see mild, manageable symptoms

Experimental studies to elucidate the beneficial effects of GLP-1 RA have mainly implicated the induction of natriuresis and the inhibition of oxidative stress, inflammation, and fibrosis [39,40,41]

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Scientists noted, "It is necessary to emphasize the importance of chewing food thoroughly when prescribing GLP-1 analogues." The analysis suggests that particular caution is needed for elderly patients or those who have problems with chewing or swallowing, or whose intestines have a reduced ability to move food