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In the real world, it generally involves using doses lower than the established therapeutic amount needed to achieve the intended medical benefit

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Resmetirom provides significant low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B (ApoB) reduction along with early hepatic antifibrotic effects, whereas semaglutide leads to substantial weight loss and wide-ranging cardiometabolic improvements

CGM: continuous glucose monitoring