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Cardiovascular outcome trials (CVOTs) of GLP-1RAs To date, the REWIND study has demonstrated for the first time that primary cardiovascular prevention strategies can significantly reduce cardiovascular adverse events in patients with T2DM, regardless of whether or not these patients are co-diagnosed with CVD [23]

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Sankey diagram, from Lambourg et al , Am J Kidney Dis, 2025 All cause mortality and MACE During the follow-up, 1702 patients died