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doi: 10.1002/ejhf.657

Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes

Then, the researchers administered exendin-4 via intrathecal injection to the experimental rats and observed a reduction in pain sensitivity, alleviation of neural inflammation, and suppression of inflammatory factors such as IL-1, TNF-, and iNOS

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Several trials involving psoriatic patients treated with GLP-1 RAs for approved indications have shown beneficial effects in improving psoriasis severity [10]