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A recent multicenter international phase II RCT (GOLDEN-505) in noncirrhotic biopsy-proven NASH patients showed an insignificant difference in NASH resolution without fibrosis progression between the elafibranor and placebo groups at 52 weeks of treatment

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As such, the clinical relevance of the active ingredients reviewed remains unclear for specific populations using GLP-1RA

Access this article Similar content being viewed by others References Feigin VL, Abajobir AA, Abate KH, Abd-Allah F, Abdulle AM, Abera SF, et al

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CrossRef Nonalcoholic fatty liver disease and bariatric surgery in adolescents AiXuan Holterman, Juan Gurria, Smita Tanpure, Nerina DiSomma Seminars in Pediatric Surgery.2014