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In the largest comparative effectiveness study of tirzepatide (Mounjaro) and semaglutide (Ozempic) for weight loss using real-world data now published in JAMA Internal Medicine Truveta Research found that patients with overweight or obesity taking tirzepatide were three times more likely to achieve 15% weight loss than those taking semaglutide

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Benef Microbes, 5:411-455

However, a growing number of patients encounter a final hurdle: loose, hanging skin

Semaglutide has two absolute contraindications: personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type...