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Some of the most commonly reported include: Gastrointestinal issues Nausea, vomiting, diarrhoea, constipation, bloating, or abdominal discomfort

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For those who have plateaued on semaglutide or want maximal weight loss potential, switching between the two medications is possible under provider guidance, and IVIM dose conversion protocols make the transition smoother

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They share the same receptor target and produce the same downstream effects: appetite suppression via hypothalamic signaling, delayed gastric emptying, enhanced glucose-dependent insulin secretion, and suppressed inappropriate glucagon release