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The importance of further studies to better understand the role of GLP-1 RAs on thyroid function and to delineate the underlying mechanisms of this complex interaction is evident

Individuals taking a GLP-1 receptor agonist were 9.1 times more likely to experience pancreatitis, 4.2 times more likely to have a bowel obstruction, and 3.7 times more likely to have gastroparesis compared to patients taking another type of drug

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Furthermore, the role of PEPT1 in intestinal inflammation remains controversial, since there is conflicting data on expression levels under inflammatory conditions in mice and humans (43, 45, 46)