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GLP-1 medications help many individuals achieve weight loss and metabolic improvements, but response varies significantly based on genetics, baseline health status, and individual physiology

Learn how ESG combined with semaglutide or tirzepatide may support medical weight loss and long-term metabolic health under physician supervision.

Adults and children 6 years and older take 2 chews, up to 4 per day

Method We systematically searched PubMed and Embase from inception to 1 May 2025 for cohort studies comparing the effect of combination therapy with SGLT2 inhibitor or GLP-1 RA monotherapy on (cardiovascular) mortality and cardiovascular or kidney endpoints in individuals with type 2 diabetes