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Dual peptides for the treatment of obesity Tirzepatide, a novel dual GIP and GLP-1RA, offers significant insights into its mechanism of action, therapeutic benefits, and clinical applications for the management of T2D and obesity in general practice

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[DOI] [PubMed] [Google Scholar] 18.Arkan M.C., Hevener A.L., Greten F.R., Maeda S., Li Z.W., Long J.M., Wynshaw-Boris A., Poli G., Olefsky J., Karin M

GLP-1 receptor agonists are designed to resist rapid enzymatic degradation, thereby allowing sustained receptor activation