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In T2D, loss of the suppressive effects of glucagon and insulin is associated with hyperglucagonaemia and this is thought to contribute to hyperglycaemia (4750)

However, high discontinuation rates, driven primarily by gastrointestinal adverse events, posed a significant barrier to achieving these outcomes

What This Means If Youre Choosing a Treatment Path Both surgery and GLP-1s help with weight and cardiometabolic risk

Patients with Hashimoto's require careful monitoring as weight changes may affect levothyroxine requirements, and GLP-1 medications carry risks including pancreatitis and gallbladder disease

These dietary recommendations are also commonly advised for patients using other GLP-1 therapies such as Ozempic, Wegovy, and Mounjaro

To manage these shortages, Australian doctors and pharmacies are being asked not to start new patients on Ozempic and to prioritise it for patients with type 2 diabetes who are already stabilised on this medicine