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Originally developed to treat type 2 diabetes (T2D), these drugs have since delivered major advances in managing obesity and cardiovascular risk reduction

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Peptide Sciences semaglutide has caveats despite strong multi-lab purity evidence: two near-threshold purity misses and repeated underfill, including -28%

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Fasting triggers modest increases in GLP-1 secretion, but the rise is typically insufficient for meaningful weight loss in most people

Among T2DM patients on antipsychotics, more patients in the combination group achieved weight loss5% within the study period compared to metformin monotherapy