mechanism of action of glp 1 Frontiers GLP-1 Agonists in Cardiovascular Diseases:

Trulicity was first approved in 2014 in the US for treating Type 2 diabetes

Mechanism Although the exact mechanisms underlying GLP-1 RA-induced diabetic retinopathy remain unclear, several hypotheses have been proposed

They also slow down gastric emptying, which moderates the rise in blood glucose levels after meals by delaying the entry of food into the small intestine

GLP-1 is also known to promote satiety and inhibit gastric emptying, acid secretion, and motility in the stomach

Here are some of the fundamental aspects of these two systems of medicine

Nat Rev Endocrinol 8(12):728742 Davies MJ, Bain SC, Atkin SL, Rossing P, Scott D, Shamkhalova MS et al (2015) Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL): a randomized clinical trial