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The same trial's main insulin-sensitivity endpoint was null for the group as a whole, with benefits concentrated in subgroups, so the honest reading is that the GLP-1 finding is real but the overall metabolic picture is mixed
LINGVAY, Ildiko et al
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Im now squarely in pre-college weight, lift 1x body weight, went up a climbing grade (this is likely just a function of time and climbing experience), probably lost some muscle but likely lost more fat because my proportions are still the same, just a bit smaller
These mechanisms together reduce daily calorie intake by 300500 calories on average, driving the 1015% weight loss seen in the first year
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