zepbound vs retatrutide tirzepatide for weight loss π Weight Loss Medications 101:
Description
Despite Harvard Medical School research published in July 2024 showing diabetes patients prescribed semaglutide faced over four times higher NAION risk (and weight loss patients faced over seven times higher risk) Novo Nordisks current Ozempic and Wegovy labels still mention only generic vision changes without specifically identifying NAION or permanent blindness as known risks
Metabolomic profiling reveals Retatrutide reduces pathways associated with insulin resistance, including sphingolipid metabolism and dicarboxylate metabolismbiomarkers strongly linked to type 2 diabetes pathogenesis

5.6% reported using them for 12 months

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At multivariate Cox regression analysis, diabetes duration (HR 1.08, 95% CI 1.021.14, P = 0.008) was the independent risk factor, and GLP-1 RAs therapy (HR 0.42, 95% CI: 0.200.88, P = 0.022) was the independent protective factor for the occurrence of MACEs in this population

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