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Glucagon suppression (reduces glucose production in the liver)
GLP-1, or glucagon-like peptide-1, is a naturally occurring hormone in the body that plays a crucial role in regulating blood sugar levels and promoting feelings of fullness or satiety after meals
Clinical Gastroenterology and Hepatology : The Official Clinical Practice Journal of the American Gastroenterological Association, 20 (3), 546558.e5
Factors accelerating tolerance include consistent calorie restriction without adequate protein, insufficient water intake, sedentary behavior, and rapid dose escalation followed by long plateaus at a single dose
Just as important, medication is never prescribed automatically
