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Wegovy can cause nausea, especially during dose increases

Do not inject into muscle or vein

Cross-Trial Context# Retatrutide's 24.2% weight loss at 48 weeks appears numerically superior to semaglutide's 14.9% at 68 weeks, but several factors complicate direct comparison: Trial phase : Phase 2 trials often yield more favorable results than Phase 3 (smaller, more controlled populations) Treatment duration : Semaglutide data are at 68-104 weeks

Microdosing, by contrast, involves maintaining doses below these established starting points or progressing more slowly than recommended

British Journal of Pharmacology, 176(Suppl 1), S21S141

No single data point should drive a strategic decision