dual glp 1 glucagon receptor agonists Machine learning designs new GCGR/GLP-1R with enhanced biological potency Polyagonists Enable Increasingly Effective Treatment
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[DOI] [PubMed] [Google Scholar] 126.Mody R, et al

Activation of glucagon-like peptide-1 receptor ameliorates cognitive decline in type 2 diabetes mellitus through a metabolism-independent pathway
It also lessened ischemia-reperfusion injury induced endothelial dysfunction in humans through the activation of K ATP channels [80]

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50,51 As expected, cinchonine dose-dependently reduced body weight gain in ob/ob-GAN NASH mice, which was consistent with decreased food intake

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