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Given that potentially dangerous islet cell hyperplasia is reported to occur in some T2DM patients treated with GLP-1R agonists, 79 it might be possible to design allosteric modulators of the GLP-1R that preferentially stimulate insulin secretion rather than islet growth

Gallstones can block bile ducts and lead to a type of jaundice called obstructive jaundice

It signals your brain that food arrived, slows stomach emptying, and triggers insulin release from the pancreas

This is how many real-life problems start: a few days of not being able to eat or drink much, then feeling lightheaded, falling, or needing emergency care for dehydration