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The rate of antibody formation is quite high in some short-acting or non-human-homologous peptides: Lixisenatide: 69.8% antibody formation incidence Exenatide: 44% antibody formation incidence Liraglutide: 8.6% antibody formation incidence Albiglutide: 4% antibody formation incidence Dulaglutide: 1.6% antibody formation incidence While these antibodies rarely neutralize the therapeutic efficacy of the compound, they can occasionally correlate with localized skin reactions

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