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Description
PMCID: PMC8419463
For thyroid C-cell tumors specifically, the FDA requires a boxed warningthe agency's strongest safety warningfor several products including semaglutide (Ozempic, Wegovy, Rybelsus), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), exenatide extended-release (Bydureon BCise), and tirzepatide (Mounjaro, Zepbound)
Diarrhea and constipation occur due to slowed intestinal transit and reduced enzyme secretion
The drugs success contributed to AbbVies decision to raise its full-year adjusted earnings guidance, reflecting confidence in Rinvoqs continued growth trajectory
& Tuttle, K.R
The gastrointestinal side effect profile is consistent with other GLP-1 based therapies
