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Initially, it was a modest tool in the diabetes arsenal: enhanced insulin release, suppressed glucagon, slowed gastric emptying

doi:10.1007/s00404-020-05450-4 Yu Y, Hao G, Zhang Q, et al

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Viele Expertinnen und Experten sehen diese Entwicklung kritisch: Sie weisen darauf hin, dass GLP-1 Analoga starke Nebenwirkungen haben knnen und noch wenige Langzeitdaten vorliegen 13

Comorbidity burden strongly influences uptake

After propensity score matching, there was no significant difference found for the risk of oral steroid use (aOR: 0.81, 95% CI: 0.481.36), intravenous steroid use (aOR: 0.69, 95% CI: 0.291.61), the need to initiate advanced therapy (aOR: 1.03, 95% CI: 0.412.60), or the risk of any-cause emergency department visits (aOR: 0.92 (0.521.61) at one year between the semaglutide-treated and non-semaglutide-treated IBD patients