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Futile lipid cycling: from biochemistry to physiology

GLP-1MK-801 did not elicit pica behaviour in Sprague Dawley rats

Weight loss outcomes vary based on individual health factors, adherence to treatment, lifestyle changes, and consistency

Interestingly, in ex vivo studies from human tissue, the duodenum and ileum but not the colon were found to be glucose responsive (218) which is different than what is reported in mouse colon (178, 191) but are consistent with data where patients that have had colon resection have normal GLP-1 responses to glucose (185)

Spend a few minutes on social media sites like TikTok and Instagram and youll find people talking about their experiences losing weight on GLP-1s and offering advice on how others can do it too

Im an annual subscriber because I felt the benefits were worth the cost