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While mild nausea and early satiety are expected and generally manageable, patients should seek immediate medical attention for severe or persistent vomiting, severe abdominal pain (especially if radiating to the back), right upper quadrant pain with fever or jaundice, or inability to maintain adequate hydration

The company intends to broaden its applications to include not only diabetes but also obesity and NASH (non-alcoholic steatohepatitis)

If You Experience Severe Diarrhea Symptoms, Such as Frequent Watery Stools, Severe Dehydration, Stomach Pain, or Signs of Bowel Obstruction (Like Severe Abdominal Swelling or Inability to Pass Gas or Stool), Seek Medical Attention Right Away

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However, serious adverse effects can occur, including pancreatitis (severe persistent abdominal pain), gallbladder disease, and acute kidney injury (typically related to dehydration from gastrointestinal symptoms)

The caveat to this is for women with known cardiovascular disease or other comorbidities, a lower blood pressure goal should be targeted closer to 120-130 mm Hg systolic over 80 mm diastolic