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Conclusion Modern peptide-based therapies offer a science-backed path to weight management when paired with expert clinical care and healthy lifestyle changes

Behav Brain Res (2012) 232(1):15964
It is also important for understanding the effect(s) of drug therapy that targets pathways and receptors that are shared between organs

One mechanism that this may be achieved is through a pathological skew toward hedonic and away from homeostatic controls of energy balance in obesity, potentially mediated by deregulated central GLP-1 signalling (a role for GLP-1 in the pathophysiology of clinical obesity)

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