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In addition, there are population groups with a greater risk of developing hyperglycemia during treatment with steroids, among these are patients with a history of gestational DM, a family history of diabetes (OR: 10.29, 95%CI: 2.33-45.54), concomitant use of mycophenolate mofetil (OR: 4.80, 95%CI: 1.32-17.45) and calcineurin inhibitors, abnormal fasting glucose, and impaired glucose tolerance[3,8,19,22]

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However, they differ in overall receptor targeting complexity and signaling pathway engagement

Users commonly complain of nausea, constipation and diarrhoea after taking the medication