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Abstract Introduction Congenital and acquired damage to hypothalamic nuclei or neuronal circuits controlling satiety and energy expenditure results in hypothalamic obesity (HO)
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Alternative pharmacological options may be considered: Orlistat : a lipase inhibitor that reduces fat absorption, available on NHS prescription or over-the-counter
Gradual titration helps the body adapt to changes in appetite and digestion
chicken, turkey) Fish Low-fat dairy (e.g
bioRxiv 2020 Sep 30 .Article 43
