glp-1 r retatrutide Triple Agonist (GLP-1/GIP/GCG) Retatrutide—A Game Changer in Obesity

Peppermint tea or peppermint oil capsules may also help relax the gut and reduce bloating

In order to create an oral version of the popular weight loss treatment, semaglutide needs to be delivered through the gastrointestinal tract without being degraded by enzymes

What are common side effects of GLP-1 therapies

Brunner said overdosing also occurs with the brand-name versions of the drugs and is not limited to compounded medications

A 2023 study out of the University of British Columbia linked GLP-1 agonists to a heightened risk of severe gastrointestinal problems. These problems include gastroparesis, pancreatitis, and bowel obstruction

The first head-to-head clinical trial (SURMOUNT-5, published in the New England Journal of Medicine in 2025) showed tirzepatide produced 20.2% average weight loss at 72 weeks compared to 13.7% for semaglutide approximately 47% greater relative weight loss