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Description
Positive findings from a phase III trial of semaglutide in metabolic dysfunction-associated steatohepatitis (MASH) is moving Novo Nordisk A/S to expand the glucagon-like peptide-1 (GLP-1) agonists indications in the U.S

Do not take if pregnant or lactating

Understanding frequency, onset timing, and individual risk factors helps guide informed decisions with your healthcare provider about treatment continuation or adjustment

Glucagon-like peptide-1(7-36)amide (GLP-1) is a 30-residue peptide hormone released from intestinal L cells following nutrient consumption

GLP-1 receptor agonists including semaglutide carry pregnancy warnings that require careful consideration if you're planning to conceive or are already pregnant

Investigational Uses Research is ongoing in: Chronic kidney disease (CKD)[6] Heart failure with preserved ejection fraction (HFpEF)[6][1] Cardiovascular outcomes in obesity[6] Preliminary HFpEF results suggest a 38% reduction in major complications vs placebo[1]
