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doi: 10.1073/pnas.0610173104

Patients should avoid fiber supplements containing sugar alcohols (sorbitol, mannitol, xylitol), as these can worsen gastrointestinal symptoms
Diabetes Care (American Diabetes Association, accessed 1 September 2024)

Understanding its current evidence base, known risks, and regulatory status is essential before considering it as a treatment option

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Concurrently, early microangiopathy and increased endothelial permeability have been identified, even in initial disease stages, marked by disrupted tight junctions and altered endothelial behavior
