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[Google Scholar] 55.Rayner CK, Wu T, Aroda VR, Whittington C, Kanters S, Guyot P, et al

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Behavioral effects: Some patients experience reduced cravings for alcohol, smoking, or even compulsive shopping

To understand how we are getting these longer-term effects, we need to study these drugs on a longer time scaleand thats exactly what we did. When the hormone GLP-1 finds a pancreatic beta cell, the ensuing chain of signals, proteins, and gene expression changes that lead to insulin secretion is very well documented

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In the field of obesity medicine, we often focus on the metabolic and cardiovascular "bonuses," but the potential for neuroprotection, specifically by reducing neuroinflammation and improving brain insulin sensitivity adds an entirely new dimension to how we view these molecules