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However, early on, it was noted that insulin derived from pancreatic extracts [1] or as crude insulin preparations [2] sometimes first elevated blood glucose and then later decreased blood glucose levels

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By the 16th week, compared with other treatment groups, the MNs/GLP-1RAs@NPs-WYRGRL group showed the most significant improvement in the clinical scores and thickness of the hind paws compared with the RA group with statistically significant difference

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Furthermore, another important motivator is the emphasis on weight management, with several GLP-1 agonists demonstrating weight loss benefits
