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Cells lining the airways and alveoli include epithelial cells and alveolar macrophages, the latter being resident innate immune cells important in surfactant recycling, protection against bacterial invasion and modulation of lung immune homeostasis
The European Cardiovascular Health Plan Roadmap from the European Alliance was published earlier in 2025 and calls for comprehensive approaches to incorporate the recognition of obesity as a trigger for cardiovascular disease

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In this article, we review the latest research to highlight when these medications might offer the greatest benefit for patients with substance use disorders.
