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For the sake of simplicity in this review, we will assume that if other microbes are present in the intestine (i.e., if conventional animals are used as the model), A
212,217,229 Thus, various approaches that target the bone microenvironment, such as bone-targeting agents, are effective for managing bone metastases in PCa (Fig
J Med Chem (2007) 50:612632
Remarkably, although immunoreactive GLP-2 had been detected in intestinal extracts of various species (refs
