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The combination of GLP-1 and GIP activation, first demonstrated with tirzepatide (Mounjaro/Zepbound), showed superior weight loss compared to GLP-1 alone

Injection site reactions : Monitoring for local reactions, proper injection technique education, and site rotation

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For now, doctors may begin considering GLP-1 medications as a dual-purpose treatment, managing blood sugar levels while potentially protecting patients from clot-related health issues

The Medication Itself GLP-1 medications stay in the tissue longer than many injections

In addition to GLP-1/GIP/GCG receptors tri-agonists, there are also triagonists targeting Xenopus GLP-1/GCG/Cholecystokinin-2 (CCK2) receptors [107], GLP-1/GCG/ neuropeptide Y 2 receptors [108], and GLP-1R, neuropeptide Y1, and neuropeptide Y2 receptors [109]