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Though both drugs reach similar maximums, retatrutides top result is a little higher in some studies

Steady calorie reduction: Unlike crash diets, calorie intake is reduced moderately, allowing patients to get enough nutrients while still losing weight

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Subsequent studies using radioimmunoassays showed that glucagon-like peptides in the intestine were released in response to glucose (5), raising the possibility that a product of the glucagon gene might function as an incretin

There have been some challenges with developing these drugs as a pill

Compounded tirzepatide is a tirzepatide product mixed by a compounding pharmacy, not the FDA-approved Lilly pen