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The primary endpoint is the semaglutideplacebo difference on change from baseline to week 104 in the Clinical Dementia Rating Sum of Boxes score

Understanding your GLP1R and GIPR pathways through biomarkers can help guide whether lifestyle alone or medical support is appropriate for your weight management goals
If left untreated, it often advances to non-alcoholic steatohepatitis, marked by inflammatory and/or fibrotic hepatic changes, leading to the eventual development of non-alcoholic fatty liver disease-related cirrhosis and hepatocellular carcinoma

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