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These compounded GLP-1 drugs may include custom microdose formulations, and some are marketed for off-label uses like longevity or cognitive support, though experts warn that their safety and effectiveness remain unproven

Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (surpass-3 MRI): A substudy of the randomised, open-label, parallel-group, phase 3 surpass-3 trial

The Subscription Trend: Telehealth GLP-1, Lemme GLP-1 and Other Services Some companies now market subscription-based GLP-1 programs directly to consumers

If you are deciding between the two medications, our semaglutide vs tirzepatide comparison and side effects comparison guide provide detailed head-to-head analyses

Women using oral contraceptives should be aware that tirzepatide may reduce the effectiveness of these medications due to delayed gastric emptying

The subgroup treated with the maximum dose of tirzepatide lost an average of 22.5% of their body weight (approximately 24 kg) and 63% of subjects lost at least 20% of their body weight