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The Bottom Line Tirzepatide wins on weight-loss efficacy in head-to-head trials

Dehydration from persistent vomiting or diarrhea can lead to dizziness, confusion, dark urine, and rapid heart rate

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All 122,124,125,126,127,128 but one 123 study showed a benefit on metabolic parameters

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Moreover, GLP-1 and the GLP-1 receptor analogs display a wide range of neuroprotective and anti-inflammatory effects in the brain in several animal models of neuroinflammatory diseases (Diz-Chaves et al., 2018