glp 1 vs weight loss surgery Bariatric Outperforms GLP-1s in GLP-1 is the new statin,

db/db mice (The Jackson Laboratory, 000697) were kept on a chow diet (Brogaarden, Altromin, 1310) and experiments were conducted on 9-week-old male mice

doi: 10.1152/ajprenal.00464.2009 88 MendisBSimpsonEMacDonaldIMansellP

Less Common but Serious Side Effects Some less common but more serious GLP-1 side effects are worth being aware of: Pancreatitis (inflammation of the pancreas) Gallbladder problems (including gallstones) Acute kidney injury (usually as a result of severe dehydration from vomiting or diarrhea) Diabetic retinopathy worsening (particularly in patients with rapid improvement in blood sugar control) Hypoglycemia (when combined with other diabetes medications like sulfonylureas or insulin) All GLP-1 medications also carry a warning regarding a theoretical risk of medullary thyroid carcinoma, based on animal studies

Curr Obes Rep 14 , 34 (2025)

Lancet Diabetes Endocrinol 9:653662

According to American Diabetes Association guidelines, diabetes is diagnosed when A1C 6.5%, fasting plasma glucose 126 mg/dL, 2-hour plasma glucose 200 mg/dL during an oral glucose tolerance test, or random plasma glucose 200 mg/dL with classic symptoms