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A person might lose 30 pounds and look modestly different in clothing, but internally, the reduction in visceral fat has transformed their metabolic health

These effects are dose-dependent and typically diminish over time

Hydration: Keep fluids up, particularly while titrating, when GI effects peak

4.4 SURPASS-4 trial comparison of tirzepatide and insulin glargine The SURPASS-4 trial included 1,995 patients with type 2 diabetes and compared tirzepatide (5 mg, 10 mg, 15 mg) with insulin glargine over 52 weeks, with the primary endpoint being the change in HbA1c (Heerspink et al., 2022)

Regular exercise increases GABA production, the brain primary calming neurotransmitter

By targeting telomere length and the pineal gland specifically, researchers believe it could slow cellular aging, improve sleep and hormonal health, boost immunity, and potentially extend healthy lifespan