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Poorly controlled blood glucose increases the risk of cardiovascular disease, nephropathy, retinopathy, and neuropathy

Dulaglutide and cardiovascular outcomes in type 2 diabetes (Rewind): a double-blind, randomised placebo-controlled trial

Clinical efficacy data is therefore extrapolated from the brand evidence rather than directly demonstrated for the compounded version

Combining increased GLP-1 with a natural DPP4 inhibitor may help the effect to last a little longer
