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More generally, the prevalence of T2DM in adults with PWS ranges from 11 to 25%, compared to 5 to 7% in the general population (189), while it is reported less than 2% in patients younger than 18 years of age (190)

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doi: 10.2337/dc13-1473

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A 104-week carcinogenicity study was conducted in male and female Sprague Dawley rats at doses of 0.075, 0.25 and 0.75 mg/kg/day liraglutide administered by bolus subcutaneous injection with exposures 0.5-, 2- and 8-times the human exposure, respectively, resulting from the MRHD based on plasma AUC comparison