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2022;13 doi: 10.3389/fimmu.2022.997578

Semaglutide and tirzepatide reduce hunger signals, increase satiety, and improve metabolic efficiency through multiple biological pathways, making them among the most effective medications available for sustainable weight management

Additionally, some foods may make controlling blood sugar levels more challenging and achieving the best possible results

Other side effects include diarrhoea (up to 30% on semaglutide and 20% on tirzepatide), vomiting (25% vs 12% respectively), constant sinusistis/pharyngitis (up to 20%), headaches (15% vs 6%), abdominal pain (10% vs 5%)

Therefore, binding of AT-04 to the target proteins can induce phagocytosis, leading to the clearance of these proteins from the body

To minimize them, doctors typically start with a low dose and gradually increase it over time