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In the SURMOUNT trials, participants experienced significant reductions in fasting insulin, HbA1c (even in non-diabetic participants), triglycerides, and blood pressure

The Central Drugs Standard Control Organisation (CDSCO) has approved its use for diabetes, but the obesity indication is still under review

People with higher starting BMIs tend to continue losing longer

If a product costs 80% less than the FDA-approved injectable while claiming equivalent results, the economics do not support genuine tirzepatide content at therapeutic concentrations

These formulations are not FDA-approved and concentrations may vary depending on the compounding pharmacy

The disadvantage is that lower doses become harder to measure accurately